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LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis

Leukocyte immunoglobulin-like receptor B (LILRB), a family of immune checkpoint receptors, contribute to acute myeloid leukemia (AML) development, but the specific mechanisms triggered by activation or inhibition of these immune checkpoints in cancer is largely unknown. Here we demonstrated that the...

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Detalles Bibliográficos
Autores principales: Wu, Guojin, Xu, Yixiang, Schultz, Robbie D, Chen, Heyu, Xie, Jingjing, Deng, Mi, Liu, Xiaoye, Gui, Xun, John, Samuel, Lu, Zhigang, Arase, Hisashi, Zhang, Ningyan, An, Zhiqiang, Zhang, Cheng Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809885/
https://www.ncbi.nlm.nih.gov/pubmed/35122056
http://dx.doi.org/10.1038/s43018-021-00262-0