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LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis
Leukocyte immunoglobulin-like receptor B (LILRB), a family of immune checkpoint receptors, contribute to acute myeloid leukemia (AML) development, but the specific mechanisms triggered by activation or inhibition of these immune checkpoints in cancer is largely unknown. Here we demonstrated that the...
Autores principales: | Wu, Guojin, Xu, Yixiang, Schultz, Robbie D, Chen, Heyu, Xie, Jingjing, Deng, Mi, Liu, Xiaoye, Gui, Xun, John, Samuel, Lu, Zhigang, Arase, Hisashi, Zhang, Ningyan, An, Zhiqiang, Zhang, Cheng Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809885/ https://www.ncbi.nlm.nih.gov/pubmed/35122056 http://dx.doi.org/10.1038/s43018-021-00262-0 |
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