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Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats

Malaria is a global health burden, with Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) responsible for the majority of infections worldwide. Circumsporozoite protein (CSP) is the most abundant protein on the surface of Plasmodium sporozoites, and antibodies targeting the central repeat region...

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Detalles Bibliográficos
Autores principales: Kucharska, Iga, Hossain, Lamia, Ivanochko, Danton, Yang, Qiren, Rubinstein, John L, Pomès, Régis, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809896/
https://www.ncbi.nlm.nih.gov/pubmed/35023832
http://dx.doi.org/10.7554/eLife.72908