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Cullin3 (CUL3) suppresses proliferation, migration and phenotypic transformation of PDGF-BB-stimulated vascular smooth muscle cells and mitigates inflammatory response by repressing Hedgehog signaling pathway

Vascular smooth muscle cell (VSMC) hyperplasia is closely associated with AS progression. Hence, it is of great significance to elucidate the molecular mechanisms underlying the involvement of VSMCs in AS. SHH antagonist can inhibit the excessive proliferation, migration and phenotypic transformatio...

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Detalles Bibliográficos
Autores principales: Xiang, Yuluan, Li, Lihua, Xia, Shuang, Lv, Jinlin, Li, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809906/
https://www.ncbi.nlm.nih.gov/pubmed/34699319
http://dx.doi.org/10.1080/21655979.2021.1995572