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Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis

We aimed to clarify the therapeutic effects of imperatorin (IMP) on knee osteoarthritis (KOA). Thirty 3-month-old SD male rats were randomly divided into Normal, monosodium iodoacetate (MIA) and MIA+IMP groups. Their synovial tissues were subjected to histopathological analysis. Primary synovial fib...

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Detalles Bibliográficos
Autores principales: Zhang, Haosheng, Ding, Liang, Shi, Xiaoqing, Mei, Wei, Huang, Zhengquan, Zhang, Li, Li, Xiaochen, Xu, Bo, Wang, Peimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809955/
https://www.ncbi.nlm.nih.gov/pubmed/34847824
http://dx.doi.org/10.1080/21655979.2021.2012949