The phosphoinositide 3-kinase inhibitor ZSTK474 increases the susceptibility of osteosarcoma cells to oncolytic vesicular stomatitis virus VSVΔ51 via aggravating endoplasmic reticulum stress

Blockage of phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) signal pathway is effective to increase the cytotoxic effects of oncolytic virus on cancer cells, but the detailed mechanisms are still largely unknown. Based on this, the present study managed to investigate the anti-tumor effects...

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Detalles Bibliográficos
Autores principales: Jiang, Jinqiong, Wang, Weida, Xiang, Weineng, Jiang, Lin, Zhou, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809975/
https://www.ncbi.nlm.nih.gov/pubmed/34720036
http://dx.doi.org/10.1080/21655979.2021.1999372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809975/
https://www.ncbi.nlm.nih.gov/pubmed/34720036
http://dx.doi.org/10.1080/21655979.2021.1999372

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