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Empagliflozin protects diabetic pancreatic tissue from damage by inhibiting the activation of the NLRP3/caspase-1/GSDMD pathway in pancreatic β cells: in vitro and in vivo studies

Diabetes mellitus is an important public health problem worldwide. Insulin deficiency caused by pancreatic β cell dysfunction is an important pathogenic factor of diabetes mellitus. This study evaluated whether empagliflozin (EMPA) protects the pancreas from diabetes mellitus-induced injury by downr...

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Detalles Bibliográficos
Autores principales: Liu, Pan, Zhang, Zhengdong, Wang, Jinwu, Zhang, Xiao, Yu, Xiaoping, Li, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810000/
https://www.ncbi.nlm.nih.gov/pubmed/34823419
http://dx.doi.org/10.1080/21655979.2021.2001240