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Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis

Ropivacaine, a common local anesthetic in the clinic, has anti-proliferative and pro-apoptotic effects in numerous cancers, however, the underlying regulatory mechanism of ropivacaine in hepatocellular carcinoma remains unclear. In the current study, human HepG2 cells were stimulated with different...

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Detalles Bibliográficos
Autores principales: Zhang, Runze, Lian, Yanhong, Xie, Kangjie, Cai, Yunfang, Pan, Yafei, Zhu, Yuntian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810031/
https://www.ncbi.nlm.nih.gov/pubmed/34696683
http://dx.doi.org/10.1080/21655979.2021.1995103