Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide

Glioblastoma (GBM) is the most common malignant primary brain tumor, and GBM patients have a poor overall prognosis. CDC20 expression is increased in a variety of tumors and associated with temozolomide (TMZ) resistance in glioma cells. Apcin specifically binds to CDC20 to inhibit APC/C-CDC20 intera...

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Detalles Bibliográficos
Autores principales: Ding, Yiming, Zhang, Chuanbao, He, Lei, Song, Xinyu, Zheng, Chengjun, Pan, Yuchu, Yu, Shuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810058/
https://www.ncbi.nlm.nih.gov/pubmed/34753395
http://dx.doi.org/10.1080/21655979.2021.2003927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810058/
https://www.ncbi.nlm.nih.gov/pubmed/34753395
http://dx.doi.org/10.1080/21655979.2021.2003927

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