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MicroRNA miR-4709-3p targets Large Tumor Suppressor Kinase 2 (LATS2) and induces obstructive renal fibrosis through Hippo signaling

Obstructive renal fibrosis is the consequence of abnormal extracellular matrix assembly, which eventually results in renal failure, acute, and end‑stage renal infection. MicroRNAs (miRNAs), a particular category of small RNAs, modulate the expression of genes post-transcriptionally and regulate biol...

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Detalles Bibliográficos
Autores principales: Jiang, Zexiang, Xia, Weiping, Dai, Guoyu, Zhang, Bo, Li, Yang, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810092/
https://www.ncbi.nlm.nih.gov/pubmed/34931960
http://dx.doi.org/10.1080/21655979.2021.2002493