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MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3

Osteoarthritis (OA) is a degenerative joint disease. Dysregulated microRNA (miRNA) expressions are implicated in OA progression. Consequently, the current study set out to investigate the mechanism of miR-140-5p in OA cartilage injury. Firstly, the murine and cell models of OA were established, and...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Qiu, Jianjun, Shi, Jixiang, Liu, Shaoyang, Zou, Hanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810115/
https://www.ncbi.nlm.nih.gov/pubmed/34565303
http://dx.doi.org/10.1080/21655979.2021.1985342