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Uncovering the action mechanism of homoharringtonine against colorectal cancer by using network pharmacology and experimental evaluation
Homoharringtonine (HHT), an Food and Drug Administration (FDA)-approved anti-leukemia drug, exerts anti-tumor activity in several solid tumors, including colorectal cancer (CRC). However, its mechanism of action in CRC progression has not been comprehensively elucidated. The drug-disease targets wer...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810123/ https://www.ncbi.nlm.nih.gov/pubmed/34847838 http://dx.doi.org/10.1080/21655979.2021.2012626 |