Knockdown of lysine (K)-specific demethylase 2B KDM2B inhibits glycolysis and induces autophagy in lung squamous cell carcinoma cells by regulating the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway

Lung squamous cell carcinoma (LUSC) is a subtype of non-small cell lung cancer with poor prognosis. This study aimed to explore the role of KDM2B in the development of LUSC. The results of this study demonstrated that KDM2B was upregulated in LUSC tissues and cell lines. Knockdown of KDM2B reduced c...

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Detalles Bibliográficos
Autores principales: Xie, Zhonghai, Li, Hongwei, Zang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810134/
https://www.ncbi.nlm.nih.gov/pubmed/34783291
http://dx.doi.org/10.1080/21655979.2021.2005931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810134/
https://www.ncbi.nlm.nih.gov/pubmed/34783291
http://dx.doi.org/10.1080/21655979.2021.2005931

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