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MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. Multiple reports have elucidated that microRNAs are promising biomarkers for AD diagnosis and treatment. Herein, the effect of miR-191-5p on microglial cell injury and the underlying mechanism were explored. APP/PS1 transgenic mice...

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Detalles Bibliográficos
Autores principales: Wan, Wenjun, Liu, Ganzhe, Li, Xia, Liu, Yu, Wang, Ying, Pan, Haisong, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810200/
https://www.ncbi.nlm.nih.gov/pubmed/34818971
http://dx.doi.org/10.1080/21655979.2021.2008638