Bacteria-enabled oral delivery of a replicon-based mRNA vaccine candidate protects against ancestral and delta variant SARS-CoV-2

The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) evolution has resulted in many variants, contributing to the striking drop in vaccine efficacy and necessitating the development of next-generation vaccines to tackle antigenic diversity. Herein we developed a multivalent Semli...

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Detalles Bibliográficos
Autores principales: Jawalagatti, Vijayakumar, Kirthika, Perumalraja, Hewawaduge, Chamith, Yang, Myeon-sik, Park, Ji-Young, Oh, Byungkwan, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810265/
https://www.ncbi.nlm.nih.gov/pubmed/35123065
http://dx.doi.org/10.1016/j.ymthe.2022.01.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810265/
https://www.ncbi.nlm.nih.gov/pubmed/35123065
http://dx.doi.org/10.1016/j.ymthe.2022.01.042

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