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Enhancement of interleukin-2 production by bovine peripheral blood mononuclear cells treated with the combination of anti-programmed death-ligand 1 and cytotoxic T lymphocyte antigen 4 chimeric monoclonal antibodies

Our previous studies demonstrate the therapeutic efficacy against bovine diseases of an anti-bovine programmed death-ligand 1 (PD-L1) chimeric antibody. In humans, PD-1 and PD-L1 antibodies are more effective when combined with an antibody targeting cytotoxic T lymphocyte antigen 4 (CTLA-4) and thes...

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Detalles Bibliográficos
Autores principales: WATARI, Kei, KONNAI, Satoru, OKAGAWA, Tomohiro, MAEKAWA, Naoya, SAJIKI, Yamato, KATO, Yukinari, SUZUKI, Yasuhiko, MURATA, Shiro, OHASHI, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810316/
https://www.ncbi.nlm.nih.gov/pubmed/34789592
http://dx.doi.org/10.1292/jvms.21-0552