Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death

Glutamine, like glucose, is a major nutrient consumed by cancer cells, yet these cells undergo glutamine starvation in the cores of tumors, forcing them to evolve adaptive metabolic responses. Pharmacologically targeting glutamine metabolism or withdrawal has been exploited for therapeutic purposes,...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Jun, Pan, Peng-yu, Sun, Ye, Wang, Jian-bo, Zhou, Huan, Xie, Xin, Duan, Zhi-yuan, Dong, Han-yu, Chen, Wen-na, Zhang, Li-de, Wang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810525/
https://www.ncbi.nlm.nih.gov/pubmed/35127502
http://dx.doi.org/10.3389/fonc.2021.794735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810525/
https://www.ncbi.nlm.nih.gov/pubmed/35127502
http://dx.doi.org/10.3389/fonc.2021.794735

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