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Deferoxamine Counteracts Cisplatin Resistance in A549 Lung Adenocarcinoma Cells by Increasing Vulnerability to Glutamine Deprivation-Induced Cell Death
Glutamine, like glucose, is a major nutrient consumed by cancer cells, yet these cells undergo glutamine starvation in the cores of tumors, forcing them to evolve adaptive metabolic responses. Pharmacologically targeting glutamine metabolism or withdrawal has been exploited for therapeutic purposes,...
Autores principales: | Liu, Wen-Jun, Pan, Peng-yu, Sun, Ye, Wang, Jian-bo, Zhou, Huan, Xie, Xin, Duan, Zhi-yuan, Dong, Han-yu, Chen, Wen-na, Zhang, Li-de, Wang, Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810525/ https://www.ncbi.nlm.nih.gov/pubmed/35127502 http://dx.doi.org/10.3389/fonc.2021.794735 |
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