Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis

Short-chain fatty acids (SCFAs) are metabolites produced mainly by the gut microbiota with a known role in immune regulation. Acetate, the major SCFA, is described to disseminate to distal organs such as lungs where it can arm sentinel cells, including alveolar macrophages, to fight against bacteria...

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Detalles Bibliográficos
Autores principales: Machado, Marina Gomes, Patente, Thiago Andrade, Rouillé, Yves, Heumel, Severine, Melo, Eliza Mathias, Deruyter, Lucie, Pourcet, Benoit, Sencio, Valentin, Teixeira, Mauro Martins, Trottein, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810543/
https://www.ncbi.nlm.nih.gov/pubmed/35126390
http://dx.doi.org/10.3389/fimmu.2022.773261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810543/
https://www.ncbi.nlm.nih.gov/pubmed/35126390
http://dx.doi.org/10.3389/fimmu.2022.773261

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