Cargando…

Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis

Short-chain fatty acids (SCFAs) are metabolites produced mainly by the gut microbiota with a known role in immune regulation. Acetate, the major SCFA, is described to disseminate to distal organs such as lungs where it can arm sentinel cells, including alveolar macrophages, to fight against bacteria...

Descripción completa

Detalles Bibliográficos
Autores principales:	Machado, Marina Gomes, Patente, Thiago Andrade, Rouillé, Yves, Heumel, Severine, Melo, Eliza Mathias, Deruyter, Lucie, Pourcet, Benoit, Sencio, Valentin, Teixeira, Mauro Martins, Trottein, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810543/ https://www.ncbi.nlm.nih.gov/pubmed/35126390 http://dx.doi.org/10.3389/fimmu.2022.773261

Ejemplares similares

Description of a Newly Isolated Blautia faecis Strain and Its Benefit in Mouse Models of Post-Influenza Secondary Enteric and Pulmonary Infections
por: Verstraeten, Sophie, et al.
Publicado: (2022)

Alteration of the gut microbiota’s composition and metabolic output correlates with COVID-19-like severity in obese NASH hamsters
por: Sencio, Valentin, et al.
Publicado: (2022)

Nuclear Receptors in the Control of the NLRP3 Inflammasome Pathway
por: Duez, Hélène, et al.
Publicado: (2021)

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters
por: Briand, François, et al.
Publicado: (2022)

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice
por: Belouzard, Sandrine, et al.
Publicado: (2022)

NLRP3/Caspase-1 inflammasome activation is decreased in alveolar macrophages in patients with lung cancer
por: Lasithiotaki, Ismini, et al.
Publicado: (2018)

Tirap controls Mycobacterium tuberculosis phagosomal acidification
por: Belhaouane, Imène, et al.
Publicado: (2023)

Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters
por: Delval, Lou, et al.
Publicado: (2023)

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
por: Xie, Min, et al.
Publicado: (2016)

Interactions between NLRP3 inflammasome and glycolysis in macrophages: New insights into chronic inflammation pathogenesis
por: Yu, Qun, et al.
Publicado: (2021)

Circadian Control of Inflammasome Pathways: Implications for Circadian Medicine
por: Pourcet, Benoit, et al.
Publicado: (2020)

Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis
por: Lee, Yoon-Mi, et al.
Publicado: (2019)

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection
por: Beshara, Ranin, et al.
Publicado: (2018)

Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition
por: Lin, Hsin-Chung, et al.
Publicado: (2020)

Suppression of NLRP3 inflammasome improves alveolar bone defect healing in diabetic rats
por: Li, Hao, et al.
Publicado: (2019)

The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes
por: Sencio, Valentin, et al.
Publicado: (2021)

The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages
por: Finucane, Orla M., et al.
Publicado: (2019)

TREM-1 governs NLRP3 inflammasome activation of macrophages by firing up glycolysis in acute lung injury
por: Zhong, Wen-Jing, et al.
Publicado: (2023)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

NLRP3 protects alveolar barrier integrity by an inflammasome-independent increase of epithelial cell adherence
por: Kostadinova, Elena, et al.
Publicado: (2016)

Diet-induced obesity and NASH aggravate SARS-CoV-2 infection in golden Syrian hamsters
por: Briand, François, et al.
Publicado: (2022)

All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage
por: Alatshan, Ahmad, et al.
Publicado: (2020)

Acetate Downregulates the Activation of NLRP3 Inflammasomes and Attenuates Lung Injury in Neonatal Mice With Bronchopulmonary Dysplasia
por: Zhang, Qian, et al.
Publicado: (2021)

Heat‐killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome
por: Fan, Hong‐Xia, et al.
Publicado: (2022)

Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome
por: Zhang, Li, et al.
Publicado: (2021)

High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages
por: Mo, Yiqun, et al.
Publicado: (2023)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Acetate attenuates inflammasome activation through GPR43-mediated Ca(2+)-dependent NLRP3 ubiquitination
por: Xu, Mengda, et al.
Publicado: (2019)

Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice
por: Chung, I-Che, et al.
Publicado: (2019)

The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing
por: Tesori, Valentina, et al.
Publicado: (2015)

Research Progress of Mitochondrial Mechanism in NLRP3 Inflammasome Activation and Exercise Regulation of NLRP3 Inflammasome
por: Zhang, Tan, et al.
Publicado: (2021)

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
por: Saresella, Marina, et al.
Publicado: (2016)

The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
por: Kim, Yang Gyun, et al.
Publicado: (2019)

Inflammasomes in Alveolar Bone Loss
por: Li, Yang, et al.
Publicado: (2021)

Regulation of glycolysis in brown adipocytes by HIF-1α
por: Basse, Astrid L., et al.
Publicado: (2017)

The role of the NLRP3 inflammasome in gout
por: Kingsbury, Sarah R, et al.
Publicado: (2011)

The Role of the NLRP3 Inflammasome in Fibrosis
por: Artlett, Carol M
Publicado: (2012)

NLRP3 Inflammasome and MS/EAE
por: Inoue, Makoto, et al.
Publicado: (2013)

NLRP3 Inflammasome and Pathobiology in AMD
por: Celkova, Lucia, et al.
Publicado: (2015)

Role of the NLRP3 inflammasome in cancer
por: Moossavi, Maryam, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_brsrjrbudmpibpnkva5uasn3n1