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A fluorescence microscopy-based protocol for volumetric measurement of lysolecithin lesion-associated de- and re-myelination in mouse brain

Lysolecithin injections into the white matter tracts of the central nervous system are a valuable tool to study remyelination, but evaluating the resulting demyelinating lesion size is challenging. Here, we present a protocol to consistently measure the volume of demyelination and remyelination in m...

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Detalles Bibliográficos
Autores principales: Bosch-Queralt, Mar, Tiwari, Vini, Damkou, Alkmini, Vaculčiaková, Lenka, Alexopoulos, Ioannis, Simons, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810560/
https://www.ncbi.nlm.nih.gov/pubmed/35141565
http://dx.doi.org/10.1016/j.xpro.2022.101141