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Automated identification of maximal differential cell populations in flow cytometry data

We introduce a new cell population score called SpecEnr (specific enrichment) and describe a method that discovers robust and accurate candidate biomarkers from flow cytometry data. Our approach identifies a new class of candidate biomarkers we define as driver cell populations, whose abundance is a...

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Detalles Bibliográficos
Autores principales: Yue, Alice, Chauve, Cedric, Libbrecht, Maxwell W., Brinkman, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810629/
https://www.ncbi.nlm.nih.gov/pubmed/34559446
http://dx.doi.org/10.1002/cyto.a.24503