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A coordinated function of lncRNA HOTTIP and miRNA-196b underpinning leukemogenesis by targeting FAS signaling

MicroRNAs (miRNAs) may modulate more than 60% of human coding genes and act as negative regulators, while long non-coding RNAs (lncRNAs) regulate gene expression on multiple levels by interacting with chromatin, functional proteins, and RNAs such as mRNAs and microRNAs. However, the crosstalk betwee...

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Detalles Bibliográficos
Autores principales: Singh, Ajeet P., Luo, Huacheng, Matur, Meghana, Eshelman, Melanie A., Hamamoto, Karina, Sharma, Arati, Lesperance, Julia, Huang, Suming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810734/
https://www.ncbi.nlm.nih.gov/pubmed/34845377
http://dx.doi.org/10.1038/s41388-021-02127-3