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Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) are promising molecules for therapeutic or prophylactic interventions. Beyond neutralization, bNAbs exert Fc-dependent functions including antibody-dependent cellular cytotoxicity and activation of the complement...

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Detalles Bibliográficos
Autores principales: Dufloo, Jérémy, Planchais, Cyril, Frémont, Stéphane, Lorin, Valérie, Guivel-Benhassine, Florence, Stefic, Karl, Casartelli, Nicoletta, Echard, Arnaud, Roingeard, Philippe, Mouquet, Hugo, Schwartz, Olivier, Bruel, Timothée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810770/
https://www.ncbi.nlm.nih.gov/pubmed/35110562
http://dx.doi.org/10.1038/s41467-022-28307-7