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The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling

Innate radioresistance substantially limits the effectiveness of radiotherapy for colorectal cancer (CRC); thus, a strategy to enhance the radiosensitivity of CRC is urgently needed. Herein, we reported that ankyrin repeat and KH domain containing 1 (ANKHD1) serves as a key regulator of radioresista...

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Detalles Bibliográficos
Autores principales: Yao, Ping-an, Wu, Yong, Zhao, Kui, Li, Yecheng, Cao, Jianping, Xing, Chungen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810793/
https://www.ncbi.nlm.nih.gov/pubmed/35110552
http://dx.doi.org/10.1038/s41419-022-04554-w