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Molecular mechanism of Arp2/3 complex inhibition by Arpin

Positive feedback loops involving signaling and actin assembly factors mediate the formation and remodeling of branched actin networks in processes ranging from cell and organelle motility to mechanosensation. The Arp2/3 complex inhibitor Arpin controls the directional persistence of cell migration...

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Detalles Bibliográficos
Autores principales: Fregoso, Fred E., van Eeuwen, Trevor, Simanov, Gleb, Rebowski, Grzegorz, Boczkowska, Malgorzata, Zimmet, Austin, Gautreau, Alexis M., Dominguez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810855/
https://www.ncbi.nlm.nih.gov/pubmed/35110533
http://dx.doi.org/10.1038/s41467-022-28112-2