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Comparison of mitochondrial DNA sequences from whole blood and lymphoblastoid cell lines

Lymphoblastoid cell lines (LCLs) provide an unlimited source of genomic DNA for genetic studies. Here, we compared mtDNA sequence variants, heteroplasmic or homplasmic, between LCL (sequenced by mitoRCA-seq method) and whole blood samples (sequenced through whole genome sequencing approach) of the s...

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Detalles Bibliográficos
Autores principales: Liu, Chunyu, Fetterman, Jessica L., Sun, Xianbang, Yan, Kaiyu, Liu, Poching, Luo, Yan, Ding, Jun, Zhu, Jun, Levy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810874/
https://www.ncbi.nlm.nih.gov/pubmed/35110616
http://dx.doi.org/10.1038/s41598-022-05814-7