Allele-specific transcription factor binding in a cellular model of orofacial clefting

Non-syndromic cleft lip with/without cleft palate (nsCL/P) is a frequent congenital malformation with multifactorial etiology. While recent genome-wide association studies (GWAS) have identified several nsCL/P risk loci, the functional effects of the associated non-coding variants are largely unknow...

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Detalles Bibliográficos
Autores principales: Ruff, Katharina L. M., Hollstein, Ronja, Fazaal, Julia, Thieme, Frederic, Gehlen, Jan, Mangold, Elisabeth, Knapp, Michael, Welzenbach, Julia, Ludwig, Kerstin U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810875/
https://www.ncbi.nlm.nih.gov/pubmed/35110662
http://dx.doi.org/10.1038/s41598-022-05876-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810875/
https://www.ncbi.nlm.nih.gov/pubmed/35110662
http://dx.doi.org/10.1038/s41598-022-05876-7

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