Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury

Itaconate, a metabolite produced during inflammatory macrophage activation, has been extensively described to be involved in immunoregulation, oxidative stress, and lipid peroxidation. As a form of iron and lipid hydroperoxide-dependent regulated cell death, ferroptosis plays a critical role in seps...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Ruyuan, Liu, Bohao, Xiong, Rui, Geng, Boxin, Meng, Heng, Lin, Weichen, Hao, Bo, Zhang, Lin, Wang, Wei, Jiang, Wenyang, Li, Ning, Geng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810876/
https://www.ncbi.nlm.nih.gov/pubmed/35110526
http://dx.doi.org/10.1038/s41420-021-00807-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810876/
https://www.ncbi.nlm.nih.gov/pubmed/35110526
http://dx.doi.org/10.1038/s41420-021-00807-3

Ejemplares similares