Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid

Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals. Despite causing a life-threatening disease, BoNT is a multipurpose therapeutic. Nevertheless, as the most potent natural toxin, BoNT is...

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Detalles Bibliográficos
Autores principales: Nowakowska, Maria B., Selby, Katja, Przykopanski, Adina, Krüger, Maren, Krez, Nadja, Dorner, Brigitte G., Dorner, Martin B., Jin, Rongsheng, Minton, Nigel P., Rummel, Andreas, Lindström, Miia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810926/
https://www.ncbi.nlm.nih.gov/pubmed/35110559
http://dx.doi.org/10.1038/s41598-022-05008-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810926/
https://www.ncbi.nlm.nih.gov/pubmed/35110559
http://dx.doi.org/10.1038/s41598-022-05008-1

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