β-III-spectrin N-terminus is required for high-affinity actin binding and SCA5 neurotoxicity

Recent structural studies of β-III-spectrin and related cytoskeletal proteins revealed N-terminal sequences that directly bind actin. These sequences are variable in structure, and immediately precede a conserved actin-binding domain composed of tandem calponin homology domains (CH1 and CH2). Here w...

Descripción completa

Detalles Bibliográficos
Autores principales: Denha, Sarah A., Atang, Alexandra E., Hays, Thomas S., Avery, Adam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810934/
https://www.ncbi.nlm.nih.gov/pubmed/35110634
http://dx.doi.org/10.1038/s41598-022-05762-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810934/
https://www.ncbi.nlm.nih.gov/pubmed/35110634
http://dx.doi.org/10.1038/s41598-022-05762-2

Ejemplares similares