Adenine overload induces ferroptosis in human primary proximal tubular epithelial cells

The pathogenesis of crystal nephropathy involves deposition of intratubular crystals, tubular obstruction and cell death. The deposition of 8-dihydroxyadenine (DHA) crystals within kidney tubules, for instance, is caused by a hereditary deficiency of adenine phosphoribosyl transferase in humans or a...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad Ali, Nag, Purba, Grivei, Anca, Giuliani, Kurt T. K., Wang, Xiangju, Diwan, Vishal, Hoy, Wendy, Healy, Helen, Gobe, Glenda, Kassianos, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810935/
https://www.ncbi.nlm.nih.gov/pubmed/35110539
http://dx.doi.org/10.1038/s41419-022-04527-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810935/
https://www.ncbi.nlm.nih.gov/pubmed/35110539
http://dx.doi.org/10.1038/s41419-022-04527-z

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