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Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

BACKGROUND: Dimethyl fumarate (DMF) is an oral immunomodulatory drug used in the treatment of autoimmune diseases. Here, we sought to study whether the effect of DMF can be detected using positron emission tomography (PET) targeting the 18-kDa translocator protein (TSPO) in the focal delayed-type hy...

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Detalles Bibliográficos
Autores principales: Vainio, S. K., Dickens, A. M., Matilainen, M., López-Picón, F. R., Aarnio, R., Eskola, O., Solin, O., Anthony, D. C., Rinne, J. O., Airas, L., Haaparanta-Solin, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811048/
https://www.ncbi.nlm.nih.gov/pubmed/35107664
http://dx.doi.org/10.1186/s13550-022-00878-y