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Effects of aging on protein expression in mice brain microvessels: ROS scavengers, mRNA/protein stability, glycolytic enzymes, mitochondrial complexes, and basement membrane components

Differentially expressed (DE) proteins in the cortical microvessels (MVs) of young, middle-aged, and old male and female mice were evaluated using discovery-based proteomics analysis (> 4,200 quantified proteins/group). Most DE proteins (> 90%) showed no significant differences between the sex...

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Detalles Bibliográficos
Autores principales: Chandra, Partha K., Cikic, Sinisa, Rutkai, Ibolya, Guidry, Jessie J., Katakam, Prasad V. G., Mostany, Ricardo, Busija, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811117/
https://www.ncbi.nlm.nih.gov/pubmed/34708300
http://dx.doi.org/10.1007/s11357-021-00468-1