Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification

Vascular calcification is a cardiovascular disorder with no therapeutic options. We recently reported that o-octanoyltransferase (CROT) suppression can inhibit vascular calcification in vivo and in vitro through amelioration of mitochondrial function and fatty acid metabolism. Inhibiting calcificati...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanaka, Takeshi, Asano, Takaharu, Okui, Takehito, Kuraoka, Shiori, Singh, Sasha A., Aikawa, Masanori, Aikawa, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811128/
https://www.ncbi.nlm.nih.gov/pubmed/35127876
http://dx.doi.org/10.3389/fcvm.2021.826529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811128/
https://www.ncbi.nlm.nih.gov/pubmed/35127876
http://dx.doi.org/10.3389/fcvm.2021.826529

Ejemplares similares