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Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification

Vascular calcification is a cardiovascular disorder with no therapeutic options. We recently reported that o-octanoyltransferase (CROT) suppression can inhibit vascular calcification in vivo and in vitro through amelioration of mitochondrial function and fatty acid metabolism. Inhibiting calcificati...

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Detalles Bibliográficos
Autores principales:	Tanaka, Takeshi, Asano, Takaharu, Okui, Takehito, Kuraoka, Shiori, Singh, Sasha A., Aikawa, Masanori, Aikawa, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811128/ https://www.ncbi.nlm.nih.gov/pubmed/35127876 http://dx.doi.org/10.3389/fcvm.2021.826529

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