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GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma

BACKGROUND: Glioma is a lethal primary tumor of central nervous system. Ferroptosis is a newly identified form of necrotic cell death. Triggering ferroptosis has shown potential to eliminate aggressive tumors. GPX7, a member of glutathione peroxidase family (GPXs), has been described to participate...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Wu, Haiyang, Wang, Fanchen, Xu, Lixia, Yan, Yan, Tong, Xiaoguang, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811259/
https://www.ncbi.nlm.nih.gov/pubmed/35127512
http://dx.doi.org/10.3389/fonc.2021.802124