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Microglia-Derived Exosomal microRNA-151-3p Enhances Functional Healing After Spinal Cord Injury by Attenuating Neuronal Apoptosis via Regulating the p53/p21/CDK1 Signaling Pathway

Spinal cord injury (SCI) is a catastrophic event mainly involving neuronal apoptosis and axonal disruption, and it causes severe motor and sensory deficits. Due to the complicated pathological process of SCI, there is currently still a lack of effective treatment for SCI. Microglia, a type of immune...

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Detalles Bibliográficos
Autores principales: Li, Chengjun, Qin, Tian, Liu, Yudong, Wen, Haicheng, Zhao, Jinyun, Luo, Zixiang, Peng, Wei, Lu, Hongbin, Duan, Chunyue, Cao, Yong, Hu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811263/
https://www.ncbi.nlm.nih.gov/pubmed/35127706
http://dx.doi.org/10.3389/fcell.2021.783017