Impact of PBP4 Alterations on β-Lactam Resistance and Ceftobiprole Non-Susceptibility Among Enterococcus faecalis Clinical Isolates

Penicillin-resistance among Enterococcus faecalis clinical isolates has been recently associated with overexpression or aminoacidic substitutions in low-affinity PBP4. Ceftobiprole (BPR), a new-generation cephalosporin, is a therapeutic option against E. faecalis. Here, we present evidence that pbp4...

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Detalles Bibliográficos
Autores principales: Lazzaro, Lorenzo M., Cassisi, Marta, Stefani, Stefania, Campanile, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811369/
https://www.ncbi.nlm.nih.gov/pubmed/35127564
http://dx.doi.org/10.3389/fcimb.2021.816657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811369/
https://www.ncbi.nlm.nih.gov/pubmed/35127564
http://dx.doi.org/10.3389/fcimb.2021.816657

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