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Prediction of Protein–Protein Interactions Between Alsin DH/PH and Rac1 and Resulting Protein Dynamics

Alsin is a protein of 1,657 amino acids known for its crucial role in vesicular trafficking in neurons thanks to its ability to interact with two guanosine triphosphatases, Rac1 and Rab5. Evidence suggests that Rac1 can bind Alsin central region, composed by a Dbl Homology (DH) domain followed by a...

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Detalles Bibliográficos
Autores principales: Cannariato, Marco, Miceli, Marcello, Cavaglià, Marco, Deriu, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811474/
https://www.ncbi.nlm.nih.gov/pubmed/35126051
http://dx.doi.org/10.3389/fnmol.2021.772122