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Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers

BACKGROUND: Despite unprecedented benefit from immune checkpoint inhibitors (ICIs) in patients with mismatch repair deficient (dMMR)/microsatellite instability high (MSI-H) advanced gastrointestinal cancers, a relevant proportion of patients shows primary resistance or short-term disease control. Si...

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Detalles Bibliográficos
Autores principales: Fucà, Giovanni, Cohen, Romain, Lonardi, Sara, Shitara, Kohei, Elez, Maria Elena, Fakih, Marwan, Chao, Joseph, Klempner, Samuel J, Emmett, Matthew, Jayachandran, Priya, Bergamo, Francesca, García, Marc Díez, Mazzoli, Giacomo, Provenzano, Leonardo, Colle, Raphael, Svrcek, Magali, Ambrosini, Margherita, Randon, Giovanni, Shah, Aakash Tushar, Salati, Massimiliano, Fenocchio, Elisabetta, Salvatore, Lisa, Chida, Keigo, Kawazoe, Akihito, Conca, Veronica, Curigliano, Giuseppe, Corti, Francesca, Cremolini, Chiara, Overman, Michael, Andre, Thierry, Pietrantonio, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811606/
https://www.ncbi.nlm.nih.gov/pubmed/35110358
http://dx.doi.org/10.1136/jitc-2021-004001