Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence

During embryonic development, hematopoiesis occurs through primitive and definitive waves, giving rise to distinct blood lineages. Hematopoietic stem cells (HSCs) emerge from hemogenic endothelial (HE) cells, through endothelial‐to‐hematopoietic transition (EHT). In the adult, HSC quiescence, mainte...

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Detalles Bibliográficos
Autores principales: Oburoglu, Leal, Mansell, Els, Canals, Isaac, Sigurdsson, Valgardur, Guibentif, Carolina, Soneji, Shamit, Woods, Niels‐Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811648/
https://www.ncbi.nlm.nih.gov/pubmed/34914165
http://dx.doi.org/10.15252/embr.202154384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811648/
https://www.ncbi.nlm.nih.gov/pubmed/34914165
http://dx.doi.org/10.15252/embr.202154384

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