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Unexpected gene activation following CRISPR‐Cas9‐mediated genome editing

The discovery of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and its development as a genome editing tool has revolutionized the field of molecular biology. In the DNA damage field, CRISPR has brought an alternative to induce endogenous double‐strand breaks (DSBs) at desir...

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Detalles Bibliográficos
Autores principales: Manjón, Anna G, Linder, Simon, Teunissen, Hans, Friskes, Anoek, Zwart, Wilbert, de Wit, Elzo, Medema, René H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811649/
https://www.ncbi.nlm.nih.gov/pubmed/34927791
http://dx.doi.org/10.15252/embr.202153902