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Association of Generalized Anxiety Disorder With Autonomic Hypersensitivity and Blunted Ventromedial Prefrontal Cortex Activity During Peripheral Adrenergic Stimulation: A Randomized Clinical Trial

IMPORTANCE: β-Adrenergic stimulation elicits heart palpitations and dyspnea, key features of acute anxiety and sympathetic arousal, yet no neuroimaging studies have examined how the pharmacologic modulation of interoceptive signals is associated with fear-related neurocircuitry in individuals with g...

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Detalles Bibliográficos
Autores principales: Teed, Adam R., Feinstein, Justin S., Puhl, Maria, Lapidus, Rachel C., Upshaw, Valerie, Kuplicki, Rayus T., Bodurka, Jerzy, Ajijola, Olujimi A., Kaye, Walter H., Thompson, Wesley K., Paulus, Martin P., Khalsa, Sahib S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811711/
https://www.ncbi.nlm.nih.gov/pubmed/35107563
http://dx.doi.org/10.1001/jamapsychiatry.2021.4225