A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG

The H19X‐encoded miR‐424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity, while increasing the pool of early adipocyte progenitors and...

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Detalles Bibliográficos
Autores principales: Rodríguez‐Barrueco, Ruth, Latorre, Jessica, Devis‐Jáuregui, Laura, Lluch, Aina, Bonifaci, Nuria, Llobet, Francisco J., Olivan, Mireia, Coll‐Iglesias, Laura, Gassner, Katja, Davis, Meredith L., Moreno‐Navarrete, José M., Castells‐Nobau, Anna, Plata‐Peña, Laura, Dalmau‐Pastor, Miki, Höring, Marcus, Liebisch, Gerhard, Olkkonen, Vesa M., Arnoriaga‐Rodríguez, Maria, Ricart, Wifredo, Fernández‐Real, José M., Silva, José M., Ortega, Francisco J., Llobet‐Navas, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811811/
https://www.ncbi.nlm.nih.gov/pubmed/34898027
http://dx.doi.org/10.1002/advs.202104759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811811/
https://www.ncbi.nlm.nih.gov/pubmed/34898027
http://dx.doi.org/10.1002/advs.202104759

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