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A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG
The H19X‐encoded miR‐424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity, while increasing the pool of early adipocyte progenitors and...
Autores principales: | Rodríguez‐Barrueco, Ruth, Latorre, Jessica, Devis‐Jáuregui, Laura, Lluch, Aina, Bonifaci, Nuria, Llobet, Francisco J., Olivan, Mireia, Coll‐Iglesias, Laura, Gassner, Katja, Davis, Meredith L., Moreno‐Navarrete, José M., Castells‐Nobau, Anna, Plata‐Peña, Laura, Dalmau‐Pastor, Miki, Höring, Marcus, Liebisch, Gerhard, Olkkonen, Vesa M., Arnoriaga‐Rodríguez, Maria, Ricart, Wifredo, Fernández‐Real, José M., Silva, José M., Ortega, Francisco J., Llobet‐Navas, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811811/ https://www.ncbi.nlm.nih.gov/pubmed/34898027 http://dx.doi.org/10.1002/advs.202104759 |
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