Nasally-delivered interferon-λ protects mice against upper and lower respiratory tract infection of SARS-CoV-2 variants including Omicron

Although vaccines and monoclonal antibody countermeasures have reduced the morbidity and mortality associated with SARS-CoV-2 infection, variants with constellations of mutations in the spike gene threaten their efficacy. Accordingly, antiviral interventions that are resistant to further virus evolu...

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Detalles Bibliográficos
Autores principales: Chong, Zhenlu, Karl, Courtney E., Halfmann, Peter J., Kawaoka, Yoshihiro, Winkler, Emma S., Yu, Jinsheng, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811897/
https://www.ncbi.nlm.nih.gov/pubmed/35118466
http://dx.doi.org/10.1101/2022.01.21.477296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811897/
https://www.ncbi.nlm.nih.gov/pubmed/35118466
http://dx.doi.org/10.1101/2022.01.21.477296

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