Cargando…
Nasally-delivered interferon-λ protects mice against upper and lower respiratory tract infection of SARS-CoV-2 variants including Omicron
Although vaccines and monoclonal antibody countermeasures have reduced the morbidity and mortality associated with SARS-CoV-2 infection, variants with constellations of mutations in the spike gene threaten their efficacy. Accordingly, antiviral interventions that are resistant to further virus evolu...
Autores principales: | Chong, Zhenlu, Karl, Courtney E., Halfmann, Peter J., Kawaoka, Yoshihiro, Winkler, Emma S., Yu, Jinsheng, Diamond, Michael S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811897/ https://www.ncbi.nlm.nih.gov/pubmed/35118466 http://dx.doi.org/10.1101/2022.01.21.477296 |
Ejemplares similares
-
Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron
por: Chong, Zhenlu, et al.
Publicado: (2022) -
Interferon-λ: Immune Functions at Barrier Surfaces and Beyond
por: Lazear, Helen M., et al.
Publicado: (2015) -
Interferon-λs: Front-Line Guardians of Immunity and Homeostasis in the Respiratory Tract
por: Andreakos, Evangelos, et al.
Publicado: (2017) -
Interferon-λ at the Center of the Storm
por: Hendricks, Matthew R., et al.
Publicado: (2020) -
Nasal commensal Staphylococcus epidermidis enhances interferon-λ-dependent immunity against influenza virus
por: Kim, Hyun Jik, et al.
Publicado: (2019)