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Structural Insights into Methylated DNA Recognition by the Methyl-CpG Binding Domain of MBD6 from Arabidopsis thaliana

[Image: see text] Cytosine methylation is an epigenetic modification essential for formation of mature heterochromatin, gene silencing, and genomic stability. In plants, methylation occurs not only at cytosine bases in CpG but also in CpHpG and CpHpH contexts, where H denotes A, T, or C. Methyl-CpG...

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Detalles Bibliográficos
Autores principales: Mahana, Yutaka, Ohki, Izuru, Walinda, Erik, Morimoto, Daichi, Sugase, Kenji, Shirakawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811898/
https://www.ncbi.nlm.nih.gov/pubmed/35128234
http://dx.doi.org/10.1021/acsomega.1c04917