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Copper-Free Alternatives to Access Ketone Building Blocks from Grignard Reagents
[Image: see text] Grignard reactions are an efficient way to form carbon–carbon bonds with widespread applications in large-scale processes. Classically, the electrophiles of choice to form ketones from Grignard reagents are acid chlorides. The reactions are typically catalyzed by additives such as...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811905/ https://www.ncbi.nlm.nih.gov/pubmed/35128268 http://dx.doi.org/10.1021/acsomega.1c06202 |