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Copper-Free Alternatives to Access Ketone Building Blocks from Grignard Reagents

[Image: see text] Grignard reactions are an efficient way to form carbon–carbon bonds with widespread applications in large-scale processes. Classically, the electrophiles of choice to form ketones from Grignard reagents are acid chlorides. The reactions are typically catalyzed by additives such as...

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Detalles Bibliográficos
Autores principales: Taeschler, Christoph, Kirchner, Eva, Păunescu, Emilia, Mayerhöffer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811905/
https://www.ncbi.nlm.nih.gov/pubmed/35128268
http://dx.doi.org/10.1021/acsomega.1c06202